Mesothelioma Antibody (HBME-1)

Immunohistochemistry-Paraffin: Mesothelioma Antibody (HBME-1) [NBP1-22828] - Formalin fixed paraffin embedded human mesothelioma stained with Mesothelioma antibody (NBP1-22828).

• Reactivity: Hu
• Applications: IHC
• Clone: HBME-1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

Mesothelioma Antibody (HBME-1) Summary

• Description: This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
• Immunogen: BALB/C mice were injected with suspension of human mesothelioma cells from patients with malignant epithelial mesothelioma.
• Localization: Cell membrane
• Specificity: This reacts with an unknown antigen on microvilli of mesothelioma cells. It stains normal mesothelial cells and epithelial mesotheliomas in a thick membrane pattern due to abundant lung microvilli on the surface of these cells.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: MMS
• Purity: IgM purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:15-1:25
  • Immunohistochemistry-Paraffin 1:15-1:25
• Application Notes: IHC-P: recommended pretreatment of citrate buffer, pH 6.0. Recommended incubation time of 30 min at RT.

Reactivity Notes

Human.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: PBS (pH 7.4), 0.2% BSA, Tween-20
• Preservative: 0.05% Sodium Azide
• Purity: IgM purified

Alternate Names for Mesothelioma Antibody (HBME-1)

• Malignant mesothelioma, susceptibility to

Background

Mesothelioma is a rare form of carcinoma of the mesothelial cells which that normally line the body cavities, including the pleura, peritoneum, pericardium, and testis. It may be localized or diffuse. Most, but not all, cases of pleural malignant mesothelioma are associated with asbestos exposure.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MMS