mes-2 Antibody

Product Discontinued

mes-2 Antibody Summary

• Immunogen: In vivo generated recombinant protein fragment MES-2.
• Specificity: This MES2 antibody is specific for C. Elegans MES2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: MES2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: This product is useful in ELISA and Western Blot.

Reactivity Notes

C. elegans

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
• Preservative: No Preservative
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

These C. elegans antibodies were generated in the labs of Jason Lieb, Susan Strome, Julie Ahringer, Arshad Desai, and Abby Dernburg.

Alternate Names for mes-2 Antibody

• Histone-lysine N-methyltransferase
• mes-2
• R06A4.7

Background

The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities. [supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for mes-2 Antibody (38570002)(2)

Publications using 38570002

• Garrison C, Lastwika K, Zhang Y et al. Proteomic Analysis, Immune Dysregulation, and Pathway Interconnections With Obesity J Proteome Res. 2017-01-06 [PMID: 27769113] (MiAr)
  
  Details:
  Analysis is performed on plasma proteomic data to identify how obesity can alter pathways and to highlight the risk factor for disease in subjects with a high body mass index.
• Rho JH, Lampe PD. High-throughput screening for native autoantigen-autoantibody complexes using antibody microarrays J Proteome Res. 2013-05-03 [PMID: 23541305] (MiAr)
  
  Details:
  A novel method using antibody microarrays is used to detect autoantibody-antigen complexes that can potentially be useful for detection and characterization of diseases.

FAQs for mes-2 Antibody (38570002). (Showing 1 - 1 of 1 FAQs).

1. I just ordered and received from you the mes-2 antibody (catalog # 38570002). on the product sheet, it lists under immunogen in vivo recombinant protein fragment MES-3. Is this incorrect, and the immunogen was actually a recombinant fragment of MES-2?
   • We distribute catalog # 38570002 for SDIX and we added the information to our datasheet exactly the way it was provided to us by SDIX; the immunogen was a recombinant Mes-2 protein fragment generated in cells as opposed to synthesized in vitro.

Bioinformatics

• Gene Symbol: MES2
• Entrez:
  • 175096(C. elegans)
  • 182928(C. elegans)
• Uniprot:
  • O17514(C. elegans)