mes-2 Products

Description

The SET domain is a highly conserved, approximately 150-amino acid motif implicated in the modulation of chromatin structure. It was originally identified as part of a larger conserved region present in the Drosophila Trithorax protein and was subsequently identified in the Drosophila Su(var)3-9 and 'Enhancer of zeste' proteins, from which the acronym SET is derived. Studies have suggested that the SET domain may be a signature of proteins that modulate transcriptionally active or repressed chromatin states through chromatin remodeling activities. [supplied by OMIM]

Bioinformatics

Entrez	175096 C. elegans 182928 C. elegans
Uniprot	O17514 C. elegans
Alternate Names	Histone-lysine N-methyltransferase mes-2 R06A4.7