Ly49C Antibody (14B11)

Images

 
Flow Cytometry: Ly49C Antibody (14B11) [NBP1-28082] - Analysis of splenocytes by multiple staining.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
14B11
Clonality
Monoclonal
Host
Golden Syrian Hamster
Conjugate
Unconjugated
Concentration
0.5 mg/ml

Order Details

Ly49C Antibody (14B11) Summary

Immunogen
IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice
Specificity
An epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants
Isotype
IgG1
Clonality
Monoclonal
Host
Golden Syrian Hamster
Purity
Protein A or G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry <= 1 ug/10^6 cells

Reactivity Notes

Mouse.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
0.1M BBS (pH 8.2)
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
Protein A or G purified

Alternate Names for Ly49C Antibody (14B11)

  • 5E6
  • Cmv1
  • Killer cell lectin like receptor 3
  • Killer cell lectin like receptor 6
  • Killer cell lectin like receptor 8
  • Killer cell lectin like receptor 9
  • Klra3
  • Klra6
  • Klra8
  • Klra9
  • Ly49 C antigen
  • Ly49 F antigen
  • Ly49 H antigen
  • Ly49 I antigen
  • Lymphocyte antigen 49C
  • Lymphocyte antigen 49F
  • Lymphocyte antigen 49H
  • Lymphocyte antigen 49I
  • T cell surface glycoprotein Ly 49C
  • T cell surface glycoprotein Ly 49F
  • T cell surface glycoprotein Ly 49H
  • T cell surface glycoprotein Ly 49I

Background

The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains approx. 90% of NK1.1+CD3- splenocytes, and approx. 6% of CD8+ spleen cells from C57BL/6 mice. (1) The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Ly49C Antibody (NBP1-28082) (0)

There are no publications for Ly49C Antibody (NBP1-28082).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for Ly49C Antibody (NBP1-28082) (0)

There are no reviews for Ly49C Antibody (NBP1-28082). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

FAQs for Ly49C Antibody (NBP1-28082) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Contact Information

Download our Western Blot eHandbook

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our Ly49C Antibody (14B11) and receive a gift card or discount.