Ly49C Antibody (14B11) - Azide and BSA Free Summary
| Immunogen |
IL-2 activated natural killed (A-LAK) cells from C57BL/6 mice |
| Specificity |
An epitope common to the Ly49C, Ly49F, Ly49H and Ly49I allelic/splice variants |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Golden Syrian Hamster |
| Purity |
Protein A or G purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Flow Cytometry <= 1 ug/10^6 cells
|
Packaging, Storage & Formulations
| Storage |
Store at 4C. Do not freeze. |
| Buffer |
0.1M BBS (pH 8.2) |
| Preservative |
No Preservative |
| Concentration |
0.5 mg/ml |
| Purity |
Protein A or G purified |
Alternate Names for Ly49C Antibody (14B11) - Azide and BSA Free
Background
The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains approx. 90% of NK1.1+CD3- splenocytes, and approx. 6% of CD8+ spleen cells from C57BL/6 mice. (1) The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Secondary Antibodies
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Isotype Controls
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Additional Ly49C Products
Blogs on Ly49C
![Flow Cytometry: Ly49C Antibody (14B11) [NBP1-28082] - Analysis of splenocytes by multiple staining.](http://images.novusbio.com/fullsize/Ly49C-Antibody-14B11-Flow-Cytometry-NBP1-28082-img0001.jpg "Flow Cytometry: Ly49C Antibody (14B11) [NBP1-28082] - Analysis of splenocytes by multiple staining.")
