Ly49C Products

Description

The monoclonal antibody 14B11 reacts with murine Ly49C, Ly49F, Ly49H and Ly49I, members of the lectin-like homodimeric Ly49 family of cell surface receptors. (1) Mouse Ly49 receptors exhibit allelic specificity for MHC class I Ia molecules and are thought to serve to prevent natural killer (NK) cells from attacking normal cells, while allowing them to attack infected or transformed cells in which class I molecules have been down-regulated. (2) These inhibitory receptors are also expressed on a subpopulation of mouse CD8+ T cells. The 14B11 antibody stains approx. 90% of NK1.1+CD3- splenocytes, and approx. 6% of CD8+ spleen cells from C57BL/6 mice. (1) The antibody also stains 30-80% of NK1.1+CD3- splenocytes in other mouse strains tested (BALB/c, C3H, 129, SJL, AKR/J).

Bioinformatics

Alternate Names

5E6 5E6 5E6 5E6 Cmv1 Cmv1 Cmv1 Cmv1 Killer cell lectin like receptor 3 Killer cell lectin like receptor 3 Killer cell lectin like receptor 3 Killer cell lectin like receptor 3 Killer cell lectin like receptor 6 Killer cell lectin like receptor 6 Killer cell lectin like receptor 6 Killer cell lectin like receptor 6 Killer cell lectin like receptor 8 Killer cell lectin like receptor 8 Killer cell lectin like receptor 8 Killer cell lectin like receptor 8 Killer cell lectin like receptor 9 Killer cell lectin like receptor 9 Killer cell lectin like receptor 9 Killer cell lectin like receptor 9 Klra3 Klra3 Klra3 Klra3 Klra6 Klra6 Klra6 Klra6 Klra8 Klra8 Klra8 Klra8 Klra9 Klra9 Klra9 Klra9 Ly49 C antigen Ly49 C antigen Ly49 C antigen Ly49 C antigen Ly49 F antigen Ly49 F antigen Ly49 F antigen Ly49 F antigen Ly49 H antigen Ly49 H antigen Ly49 H antigen Ly49 H antigen Ly49 I antigen Ly49 I antigen Ly49 I antigen Ly49 I antigen Lymphocyte antigen 49C Lymphocyte antigen 49C Lymphocyte antigen 49C Lymphocyte antigen 49C Lymphocyte antigen 49F Lymphocyte antigen 49F Lymphocyte antigen 49F Lymphocyte antigen 49F Lymphocyte antigen 49H Lymphocyte antigen 49H Lymphocyte antigen 49H Lymphocyte antigen 49H Lymphocyte antigen 49I Lymphocyte antigen 49I Lymphocyte antigen 49I Lymphocyte antigen 49I T cell surface glycoprotein Ly 49C T cell surface glycoprotein Ly 49C T cell surface glycoprotein Ly 49C T cell surface glycoprotein Ly 49C T cell surface glycoprotein Ly 49F T cell surface glycoprotein Ly 49F T cell surface glycoprotein Ly 49F T cell surface glycoprotein Ly 49F T cell surface glycoprotein Ly 49H T cell surface glycoprotein Ly 49H T cell surface glycoprotein Ly 49H T cell surface glycoprotein Ly 49H T cell surface glycoprotein Ly 49I T cell surface glycoprotein Ly 49I T cell surface glycoprotein Ly 49I T cell surface glycoprotein Ly 49I