Kos1/Tnk1 Antibody


Western Blot: Kos1/Tnk1 Antibody [NB300-237] - T47D cells expressing GFP/GFP-Kos were lysed in RIPA lysis buffer. 500ug protein from clarified cell lysates was immunoprecipitated with an anti-GFP antibody. The washed ...read more
Immunocytochemistry/ Immunofluorescence: Kos1/Tnk1 Antibody [NB300-237] - Kos1 staining in Hela cells detected with a Dylight 488 labeled secondary antibody.

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, ICC/IF
1 mg/ml

Order Details

Kos1/Tnk1 Antibody Summary

C-terminal residues 421-434 [QNQVQSLPAGSAEP] of the 47 kDa mouse Kos1 / Tnk1 protein.
This is specific for Kos1/Tnk1
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
This antibody may be used for Western blot and immunocytochemistry/immunofluorescence.

Reactivity Notes

Mouse and human.


Kinase of embryonic stem cells (Kos1) is a nonreceptor protein tyrosine kinase (NRPTK) and a new member of the Ack family of NRPTKs. Kos1 is a ubiquitously expressed 47-kDa protein with autotyrosine kinase activity that is developmentally regulated during embryogenesis. Kos1 is also upregulated following IL3 withdrawal from factor-dependent murine NSF/N1.H7 cells that undergo apoptosis, suggesting a role in growth inhibition. Data support a negative regulatory role for Kos1 in regulating the Ras-Raf1-MAPK growth pathway by a mechanism that requires its autotyrosine kinase activity.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies


Isotype Controls

Additional Kos1/Tnk1 Antibody Products

Kos1/Tnk1 NB300-237

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