HIV-2 Nef Antibody (4B5) Summary
| Immunogen |
TrpE-Fusion protein |
| Specificity |
Recognizes HIV-2 Nef and does not cross react with HIV-1 Nef |
| Isotype |
IgG1 |
| Clonality |
Monoclonal |
| Host |
Rat |
| Purity |
Immunogen affinity purified |
| Innovator's Reward |
Test in a species/application not listed above to receive a full credit towards a future purchase. |
Applications/Dilutions
| Dilutions |
- Immunoprecipitation 1:10-1:500
- Western Blot 1:100-1:2000
|
Reactivity Notes
Packaging, Storage & Formulations
| Storage |
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles. |
| Buffer |
PBS and 30% Glycerol |
| Preservative |
0.05% Sodium Azide |
| Concentration |
1 mg/ml |
| Purity |
Immunogen affinity purified |
Alternate Names for HIV-2 Nef Antibody (4B5)
Background
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signaling.
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are
guaranteed for 1 year from date of receipt.
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Product General Protocols
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Video Protocols
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Secondary Antibodies
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Isotype Controls
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Blogs on HIV-2 Nef