HIV-1 gp120 Antibody [Janelia Fluor® 585]

Product Discontinued

HIV-1 gp120 Antibody [Janelia Fluor® 585] Summary

• Immunogen: HIV-1 gp120 antibody was raised against a peptide corresponding to 15 amino acids near the center of HIV-1 gp120. Amino Acid Squence: VAPTKAKRRVVQREKR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: env
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for HIV-1 gp120 Antibody [Janelia Fluor® 585]

• Envelope surface glycoprotein gp120
• gp120 glycoprotein
• gp120
• Human immunodeficiency virus 1
• SU
• Surface protein

Background

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: env