HIV-1 gp120 Antibody (2558)

Product Discontinued

HIV-1 gp120 Antibody (2558) Summary

• Immunogen: YNKRKRIHI for HIV protein was used as the immunogen for this antibody.
• Specificity: HIV-1
• Isotype: IgG1 Lambda
• Clonality: Monoclonal
• Host: Human
• Gene: env
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Neutralization

Packaging, Storage & Formulations

• Storage: Lyophilized antibody can be kept at 4C for up to 3 months and should be kept at -20C for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20C) or for long-term storage (-80C). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.1 ml water.

Alternate Names for HIV-1 gp120 Antibody (2558)

• Envelope surface glycoprotein gp120
• gp120 glycoprotein
• gp120
• Human immunodeficiency virus 1
• SU
• Surface protein

Background

HIV-1 gp120 is a surface glycoprotein that enables viral attachment and entry into host cells. It is also involved in neurotoxicity and has been implicated in HIV-associated neurocognitive disorders. HIV-1 gp120 also induces apoptosis in neuronal cells by signaling mitochondrial-death proteins which may upregulate the death receptor, Fas. Because HIV gp120 is necessary for HIV-1 to enter CD4 cells, gp120 is one of the main targets of HIV vaccine research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: env