Hepatitis C Virus Antibody (BGN/1244/3B5)

Product Discontinued

Hepatitis C Virus Antibody (BGN/1244/3B5) Summary

• Immunogen: Recombinant Hepatitis C NS-3 protein.
• Specificity: specific for the Hepatitis C virus non-structural protein 3 (NS3).
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:100-1:2000
• Application Notes: Western Blot, ELISA In blots, tightly packed triplets are obtained at approx. 48 kD, with a minor band at 30 kD. This reflects bands found in immunoblots using a known antibody positive serum.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Phosphate buffered saline
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Protein A purified

Alternate Names for Hepatitis C Virus Antibody (BGN/1244/3B5)

• HCV NS5
• Hepatitis C virus non structural protein 5
• Hepatitis C virus nonstructural protein 5
• Hepatitis C Virus NS5

Background

HCV is a positive, single-stranded RNA virus in the Flaviviridae family. The genome is approximately 10,000 nucleotides and encodes a single polyprotein of about 3,000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins including NS3, and several non-structural proteins necessary for viral replication. The NS3 part of the polyprotein displays three enzymatic activities: serine protease, NTPase and RNA helicase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.