HDL Native Protein

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Product Details

Summary
Product Discontinued
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Order Details


    • Catalog Number
      NBP1-99178
    • Availability
      Product Discontinued

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HDL Native Protein Summary

Description
Native HDL

Source:Human plasma
Amino Acid Sequence:(Q00341)

Source
Human Plasma
Protein/Peptide Type
Native Protein
Purity
>95%, by SDS-PAGE

Applications/Dilutions

Dilutions
  • SDS-Page
Theoretical MW
262 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C.
Buffer
152 mM NaCl, 0.01% EDTA (pH 7.4)
Purity
>95%, by SDS-PAGE

Alternate Names for HDL Native Protein

  • APOA1/APOC3 fusion gene
  • Apolipoprotein A I precursor
  • Apolipoprotein of high density lipoprotein
  • High Density Lipoprotein

Background

HDL is the vehicle for reversed cholesterol transport and estrification, serving as a scavenger for free cholesterol during intraVascular catabolism of lipoproteins. HDL levels are inversely correlated with coronary heart disease. In a normal fasting individual, HDL concentrations range from 1.0-2.0 g/L.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Additional HDL Products

Array NBP1-99178

Research Areas for HDL Native Protein (NBP1-99178)

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Blogs on HDL.

Scavenger's Helper - SR-BI (scavenger receptor class B member 1, SCARB1)
SR-B1 belongs to the CD36 scavenger receptor family and serves as a receptor for several ligands including phospholipids, cholesterol ester, lipoproteins, phosphatidylserine, and caveolae localized HDL. It is expressed in endothelial cells, macrophage...  Read full blog post.

SREBP: Gatekeeper of Cholesterol Homeostasis
SREBP1 (sterol-regulatory-element-binding protein 2) is a basic-helix-loop-helix-leucine zipper (bHLH-ZIP) transcription factor. It regulates sterol and cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. ...  Read full blog post.

SREBP2: From Cholesterol Homeostasis to Cancer Invasion
Sterol-regulatory-element-binding protein 2 (SREBP2) is a transcription factor that regulates cholesterol homeostasis by controlling enzymes involved in cholesterol synthesis and uptake, e.g. HMG-CoA. Along with another transcription factor LXR, SREBP...  Read full blog post.

LXR Alpha, ABCA1 and Cholesterol Homeostasis
LXR Alpha, also known as Liver X receptor Alpha is a 50KDa protein that belongs to the nuclear hormone receptor family located in the nucleus. It is specifically expressed in the liver, kidney and intestine; however it has also been found in the splee...  Read full blog post.

SR-BI Antibodies: A Potential for Blocking Hepatitis C Uptake
Scavenger Receptor Class B Membrane 1, also known as SR-BI plays an important role in lipid metabolism. Its main function is to mediate transfer of cholesterol between the cell surface and high density lipoprotein (HDL). HDL acts as an extracellular d...  Read full blog post.

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Calculators

Concentration Calculator

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