HBcAg Antibody (Hep2 (H69)) [Alexa Fluor™ Plus 405]

• Reactivity: V-Vi
• Applications: IHC
• Clone: Hep2 (H69)
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 405

HBcAg Antibody (Hep2 (H69)) [Alexa Fluor™ Plus 405] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Purified hepatitis B core antigen
• Specificity: NB100-64454 is specific for Hepatitis B core antigen (HBcAg).
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: C
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product NB100-64454. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Affinity purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for HBcAg Antibody (Hep2 (H69)) [Alexa Fluor™ Plus 405]

• c
• Core antigen
• HBc
• HBcAg
• Hepatitis B Virus core antigen

Background

Hepatitis B Virus Core Antigen (HBcAg) is part of the infectious virion containing an inner "core particle" enclosing the viral genome. The icosahedral core particle contains 180 or 240 copies of the core protein. HBcAg is one of the three major clinical antigens of hepatitis B virus but disappears early in the course of infection. The hepatitis B virus core antigen (HBcAg) is a highly immunogenic subviral particle and functions as both a T-cell-dependent and a T-cell-independent antigen. Therefore, HBcAg may be a promising candidate target for therapeutic vaccine control of chronic HBV infection. This antibody stains predominantly the nuclei of liver cells. Occasionally variable staining may also be seen in the perinuclear cytoplasm.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: C