Epstein Barr Virus Antibody (CS4) [DyLight 650]

• Reactivity: V-Vi
• Applications: WB, ICC/IF, IHC
• Clone: CS4
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

Epstein Barr Virus Antibody (CS4) [DyLight 650] Summary

• Immunogen: Recombinant fusion protein containing the sequence of bacterial beta-galactosidase and the carboxyl half of EBV-encoded LMP
• Localization: Nuclear
• Specificity: This antibody is a mixture of four different monoclonal antibodies. This antibody is specific to 60kDa latent membrane protein (LMP-1) encoded by the BNLF1 gene of the EBV. Each clone reacts with different epitopes on the hydrophilic C-terminus of the cytoplasmic domain of LMP-1. This antibody stains strongly with EBV-positive lymphoblastoid cell lines and EBV infected B cell immunoblasts in infectious mononucleosis. EBV, also designated human herpesvirus 4 (HHV-4), is a member of the herpesvirus family and is one of the most common human viruses. EBV infects B cells and, though often asymptomatic, it can cause infectious mononucleosis, a disease characterized by fatigue, fever, sore throat and muscle soreness.
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Reactivity Notes

EBV

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for Epstein Barr Virus Antibody (CS4) [DyLight 650]

• Epstein Barr Virus
• Human herpesvirus type 4
• Hypothetical protein BALF1

Background

Epstein Barr virus (EBV) is a member of the herpesvirus family and one of the most common human viruses. Most people become infected with EBV during their lives. Primary infections usually results in infectious mononucleosis (glandular fever) but the virus can also lay dormant in B lymphocytes and when reactivated become associated with more serious disease such as Burkitt's lymphoma, nasopharyngeal carcinoma and Hodgkin's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

FAQs for Epstein Barr Virus Antibody (NBP3-08449C). (Showing 1 - 1 of 1 FAQ).

1. I need the names of the primary and secondary antibodies used in an EBV immunohistochemical method.
   • We have the following primary antibodies for EBV that have been validated in IHC. You would then choose a secondary dependent on the host of the primary you choose - anti-rat or anti-mouse - and conjugated to the label of your choice.