DTX1/DTX4 Antibody (730612) [Alexa Fluor™ Plus 555]

• Clone: 730612
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 555

DTX1/DTX4 Antibody (730612) [Alexa Fluor™ Plus 555] Summary

• Specificity: Detects human DTX1 in direct ELISAs and Western blots. In direct ELISAs and Western blots, 100% cross-reactivity with recombinant human DTX4 is observed.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for DTX1/DTX4 Antibody (730612) [Alexa Fluor™ Plus 555]

• DTX1/DTX4
• DTX1;Fxit1;hDx-1;mKIAA4160

Background

Deltex-1 (DTX1) is an approximately 75 kDa cytoplasmic and nuclear ubiquitin ligase that interacts with the Notch-1 intracellular domain and regulates Notch-induced gene transcription. It contains two WWE domains (aa 14-94 and aa 95-171) and one RING-type zinc finger (aa 411-472). Within aa 1-147, human Deltex-1 shares 97% aa sequence identity with mouse and rat Deltex-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.