Dendritic Cell Marker Antibody (AP-MAB0801) [Janelia Fluor® 669]

• Reactivity: Mu
• Applications: Flow, IHC, CyTOF-ready
• Clone: AP-MAB0801
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Janelia Fluor 669

Dendritic Cell Marker Antibody (AP-MAB0801) [Janelia Fluor® 669] Summary

• Immunogen: Mouse Dendritic cells
• Marker: Dendritic Cell Marker
• Specificity: Reacts with mouse dendritic cells.
• Isotype: IgG2
• Clonality: Monoclonal
• Host: Rat
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for Dendritic Cell Marker Antibody (AP-MAB0801) [Janelia Fluor® 669]

• DCs
• Dendritic cell

Background

Dendritic cells are potent antigen presenting cells that possess the ability to stimulate naive T cells. They are critical for the induction of T cell responses resulting in cell mediated immunity. Within different tissues, dendritic cells differentiate and become active in the taking up and processing of antigens, and their subsequent presentation on the cell surface linked to major histocompatibility (MHC) molecules. Upon appropriate stimulation, dendritic cells undergo further maturation and migrate to secondary lymphoid tissues where they present Ag to T cells and induce an immune response.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.