Clostridium Tetani Toxoid Antibody (3F6) - BSA Free

Product Discontinued

Clostridium Tetani Toxoid Antibody (3F6) - BSA Free Summary

• Immunogen: Tetanus toxoid, formaldehyde inactivated tetanus toxin
• Epitope: Epitope specificity differs from that of Clone 14 and Clone 17 as determined by competitive ELISA.
• Specificity: Clone 3F6 binds to both tetanus toxin and tetanus toxoid
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
• Application Notes: Clone 3F6 does not neutralize tetanus toxin efficiently enough to protect mice in the in-vivo test of tetanus antitoxin activity.

Reactivity Notes

Clostridium tetani toxoid

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 10mM Phosphate (pH 7.4) and 0.5M NaCl
• Preservative: 0.09% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A or G purified

Alternate Names for Clostridium Tetani Toxoid Antibody (3F6) - BSA Free

• Clostridium tetani toxoid
• Tentoxylysin
• Tetanus toxin
• tetX

Background

Clostridium tetani is a Gram-positive, motile bacterium found in soil and animal feces. Toxigenic strains of C. tetani contain a plasmid encoding the potent exotoxin which causes tetanus (lockjaw). The toxin is synthesized as a single 150 kDa protein chain which is cleaved ("nicked") into a 100 kDa heavy chain (fragment B) and a 50 kDa light chain (fragment A) connected by a disulfide bridge. Tetanus toxoid is produced by prolonged incubation of the toxin with formaldehyde and lysine, and is often used as a carrier for compounds of poor immunogenicity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.