ChT1 antigen Antibody (CT1) - Azide and BSA Free

Flow Cytometry: ChT1 antigen Antibody (CT1) [NBP1-28355] - Chick thymocytes were stained with Mouse Anti-Chicken ChT1-FITC (SB Cat. No. 8410-02).

• Reactivity: Av, Ch
• Applications: Flow, Func, IP
• Clone: CT1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: 0.5 mg/ml

ChT1 antigen Antibody (CT1) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse ChT1 antigen Antibody (CT1) - Azide and BSA Free (NBP1-28355) is a monoclonal antibody validated for use in Flow and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Chicken thymocytes
• Specificity: Chicken/Quail ChT1
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry <= 1 ug/10^6 cells
  • Immunoprecipitation 1:10 - 1:500
  • In vitro assay

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: 0.1M BBS (pH 8.2)
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: Protein A or G purified

Alternate Names for ChT1 antigen Antibody (CT1) - Azide and BSA Free

• ChT1 thymocyte antigen
• V set and immunoglobulin domain containing
• VSIG1

Background

ChT1, a member of the Ig superfamily with one V-like and one C2-like domain, is a T cell antigen that is expressed on the surface of embryonic thymocytes (day 10). In young chickens, about 90% of the thymocytes as well as a subpopulation of peripheral lymphocytes (which represent recent thymic emigrants) are ChT1 positive.1-4 Expression in the periphery declines with age and, in correlation with partial thymectomy, indicates that ChT1 can be used as an accurate marker for studying thymic function. (3) CT1 can block T cell differentiation in vitro, in thymic organ cultures and in thymocyte precursors cultured on stromal cell monolayers. (4) CT1 also recognizes quail cortical thymocytes. (1)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.