Cholera Toxin Antibody (3D11) - BSA Free

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Product Details

Summary
Reactivity BaSpecies Glossary
Applications ELISA
Clone
3D11
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free

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Cholera Toxin Antibody (3D11) - BSA Free Summary

Description
Novus Biologicals Mouse Cholera Toxin Antibody (3D11) - BSA Free (NB200-443) is a monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
Immunogen
Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with purified beta-subunit of cholera toxin.
Epitope
B-subunit of cholera toxin
Localization
Secreted
Specificity
Specific for the beta sub-unit of cholera toxin. Reacts with cholera toxin and E. coli heat labile enterotoxin.
Isotype
IgG2b
Clonality
Monoclonal
Host
Mouse
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
PBS (pH 7.4)
Preservative
0.09% Sodium Azide
Purity
Protein A purified

Alternate Names for Cholera Toxin Antibody (3D11) - BSA Free

  • Cholera enterotoxin gamma chain
  • Cholera enterotoxin subunit A
  • Cholera enterotoxin subunit B
  • Choleragenoid
  • toxA
  • toxB

Background

The B subunit of cholera toxin (CtxB) binds to a GM1-ganglioside receptor, a ubiquitous glycolipid cell surface receptor. This binding is widely accepted to initiate toxin action by triggering uptake and delivery of the toxin A subunit into cells. The beta chain has no toxic activity by itself. The holotoxin consists of a pentameric ring of B subunits whose central pore is occupied by the A subunit. The A subunit contains two chains, A1 and A2, linked by a disulfide bridge. The A subunit (and Cholera toxin) activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

Additional Cholera Toxin Products

Array NB200-443

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