3-Nitrotyrosine Antibody (18G4)

Product Discontinued

3-Nitrotyrosine Antibody (18G4) Summary

• Immunogen: 3-Nitrotyrosine conjugated to KLH
• Specificity: 3-Nitrosylated tyrosine containing proteins in most species.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity: Multi-step

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation
  • Western Blot
• Application Notes: .

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.08% Sodium Azide
• Purity: Multi-step

Notes

Purification involved a two-step procedure, first by hydroxyapatite chromatography and the second step involved DEAE cellulose ion exchange chromatography.

Background

The presence of nitrated protein tyrosine residues can be an indicator of oxidative nitric oxide damage.3-Nitrotyrosine formed from the reaction of peroxynitrite with tyrosine is associated with inflammatory and degenerative disorders.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.