NLRP11 Products

Description

NALPs are cytoplasmic proteins that form a subfamily within the larger CATERPILLER protein family. Most short NALPs, such as NALP11, have an N-terminal pyrin (MEFV; MIM 608107) domain (PYD), followed by a NACHT domain, a NACHT-associated domain (NAD), and a C-terminal leucine-rich repeat (LRR) region. The long NALP, NALP1 (MIM 606636), also has a C-terminal extension containing a function to find domain (FIIND) and a caspase recruitment domain (CARD). NALPs are implicated in the activation of proinflammatory caspases (e.g., CASP1; MIM 147678) via their involvement in multiprotein complexes called inflammasomes (Tschopp et al., 2003 [PubMed 12563287]).[supplied by OMIM]

Bioinformatics

Product By Gene ID

204801

Alternate Names

CLR19.6 NACHT, leucine rich repeat and PYD containing 11 NALP11NACHT, LRR and PYD domains-containing protein 11 NLR family, pyrin domain containing 11 NOD17PYPAF7 Nucleotide-binding oligomerization domain protein 17 nucleotide-binding oligomerization domain, leucine rich repeat and pyrin domaincontaining 11 PAAD- and NACHT-containing protein 10 PAAD- and NACHT-containing protein 10B PAAD-and NACHT domain-containing protein 10 PAN10FLJ26273 PYPAF6NACHT, LRR and PYD containing protein 11 PYRIN-containing APAF1-like protein 6

Research Areas for NLRP11

Find related products by research area and learn more about each of the different research areas below.

Immunology
Innate Immunity

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