MUC4 Products

Description

MUC4 is a constituents of mucus, the viscous secretion that covers epithelial surfaces such as those in the trachea, colon, and cervix, and is a highly glycosylated proteins. These glycoproteins play important roles in the protection of the epithelial cells and have been implicated in epithelial renewal and differentiation. MUC4 antibody studies have shown that MUC4 encodes an integral membrane glycoprotein found on the cell surface, although secreted isoforms may exist. At least two dozen transcript variants of MUC4 have been found, although for many of them the full-length transcript has not been determined or they are found only in tumor tissues. MUC4 is expressed in a wide variety of carcinomas making MUC4 antibodies a key cancer research tool.

Bioinformatics

Entrez	4585 Human
Uniprot	NP_004523 Human Q8JZM8 Mouse Q99102 Human
Product By Gene ID	4585
Alternate Names	Ascites sialoglycoprotein ASGP HSA276359 MUC-4 mucin 4, cell surface associated mucin 4, tracheobronchial mucin-4 Pancreatic adenocarcinoma mucin Testis mucin Tracheobronchial mucin

Research Areas for MUC4

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Cancer

Related MUC4 Blog Posts

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MUC4 (Mucin-4) Mucus is the viscous secretion that covers epithelial surfaces (trachea, colon, and cervix) and consists of twenty highly glycosylated proteins called mucins. The mucin family all are high-molecular weight proteins with oligosaccharides attached to th...    Read more.

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