Lck Products

Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein is a key signaling molecule in the selection and maturation of developing T-cells. It contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to the plasma membrane and pericentrosomal vesicles, and binds to cell surface receptors, including CD4 and CD8, and other signaling molecules. Multiple alternatively spliced variants, encoding the same protein, have been described. [provided by RefSeq]

Bioinformatics

Entrez	3932 Human
Uniprot	AAH13200 Human
Product By Gene ID	3932
Alternate Names	EC 2.7.10 EC 2.7.10.2 Hck-3 Lck Lcktkr Leukocyte C-terminal Src kinase LSK LSTRA Lymphocyte cell-specific protein-tyrosine kinase lymphocyte-specific protein tyrosine kinase p56(LSTRA) protein-tyrosine kinase p56lck p56-LCK pp58lck Protein YT16 Proto-oncogene Lck proto-oncogene tyrosine-protein kinase LCK T cell-specific protein-tyrosine kinase T-lymphocyte specific protein tyrosine kinase p56lck tyrosine-protein kinase Lck YT16

Research Areas for Lck

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cell Cycle and Replication
Immunology
Signal Transduction
Tyrosine Kinases