DNMT3B Products

Antibodies
DNMT3B Antibody
DNMT3B Antibody
Species: Hu, Mu, Rt
Applications: WB, Simple Western, IHC, ChIP, Mycoplasma
Host: Rabbit Polyclonal
DNMT3B Antibody - BSA Free
DNMT3B Antibody - BSA Free
NBP1-85815
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Formulation Catalog # Availability Price  
DNMT3B Antibody (SR2574) - BS ...
DNMT3B Antibody (SR2574) - BSA Free
NBP3-27699
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Monoclonal
Formulation Catalog # Availability Price  
ELISA Kits
Human DNMT3B - Ready-To-Use ...
Human DNMT3B - Ready-To-Use ELISA...
NBP3-31444
Species: Hu
Applications: ELISA
Kits
DNMT3B Activity/Inhibition As ...
DNMT3B Activity/Inhibition Assay Kit
KA1547
Species: Hu
Applications: Func
Proteins
DNMT3B Recombinant Protein An ...
DNMT3B Recombinant Protein Antigen
NBP1-85815PEP
Species: Hu
Applications: AC

Description

This protein is required for genome wide de novo methylation and is essential for development. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in the gene cause the immunodeficiency centromeric instability-facial anomalies (ICF) syndrome.

Bioinformatics

Entrez Human
Mouse
Product By Gene ID 1789
Alternate Names
  • DNA (cytosine-5-)-methyltransferase 3 beta
  • DNA (cytosine-5)-methyltransferase 3B
  • DNA methyltransferase HsaIIIB
  • DNA MTase HsaIIIB
  • DNMT3B
  • EC 2.1.1.37
  • ICF
  • ICF1
  • M.HsaIIIB

Research Areas for DNMT3B

Find related products by research area and learn more about each of the different research areas below.

Cancer
Chromatin Research
DNA Repair
Epigenetics

Related DNMT3B Blog Posts

Check out the latest blog posts on DNMT3B.
Eat responsibly: Epigenetic downregulation of Ankrd26 gene by long-term high-fat intake promotes obesity and inflammation
By Jamshed Arslan Pharm.D. White adipose tissue (WAT) represents the primary site to store energy in humans. WAT’s endocrine regulation of energy balance is controlled by nutritional status, exercise, and hormones l...    Read more.
The role of DNMT3B in the co-incidence of methyltransferase and tumor suppressor expression in malignancies
Epigenetics is the process of heritable change in gene activity despite alteration of the hosts DNA sequence, essentially causing a change in a phenotype without a change in the genotype of a host. To change the gene sequence without interfering w...    Read more.
The role of DNMT3A in development
Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence.  Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation.  Gene silencing in DNA ...    Read more.
Go Ahead! Make My DNA
DNA methylation plays a critical role the long-term silencing of transcription and is essential for processes such as embryonic development, germline differentiation, and tissue maturation. Dnmt3a is a member of the C5-methyltransferase family that re...    Read more.
Controlling Epigenetic Signaling with Dnmt1 and Dnmt3b
Dnmt1 belongs to the C5-methyltransferase family that repairs cytosines in dsDNA using a nucleophilic attack mechanism. Dnmt1 is the most abundant mammalian DNA methyltransferase. It is the key methylation maintenance enzyme for both DNA replication/r...    Read more.
DNMT3B: Roles in Leukemia
DNA-methyltransferase 3B (DNMT3B), also known as DNA methyltransferase HsaIIIB, is a member of the class I-like SAM-binding methyltransferase superfamily and C5-methyltransferase family. DNMT3B plays an essential role in the establishment of DNA methy...    Read more.
Not as Pluripotent as You Used to Be: Embryonic Stem Cell Markers and the Aging Process
We at Novus Biologicals recently extended our antibody catalog to include several embryonic stem cells (ESC) antibodies validated for use in FACS (fluorescent activated cell sorting) assays. Among them was Oct4, which recently became the focus of an i...    Read more.
Read more DNMT3B related blogs.