ZP4 Products

Antibodies
ZP4 Antibody
ZP4 Antibody
NBP1-86823
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ZP4 Antibody
ZP4 Antibody
NBP1-69341
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Proteins
ZP4 Recombinant Protein Antig ...
ZP4 Recombinant Protein Antigen
NBP1-86823PEP
Species: Hu
Applications: AC
RNAi
ZP4 RNAi
ZP4 RNAi
H00057829-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a consensus furin cleavage site, and a C-terminal transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. Previously, this gene has been referred to as ZP1 or ZPB and thought to have similar functions as mouse Zp1. However, a human gene with higher similarity and chromosomal synteny to mouse Zp1 has been assigned the symbol ZP1 and this gene has been assigned the symbol ZP4. (provided by RefSeq)

Bioinformatics

Entrez Human
Uniprot Human
Product By Gene ID 57829
Alternate Names
  • zinc fingers and homeoboxes protein 1
  • zinc fingers and homeobox 1
  • zinc finger and homeodomain protein 1
  • zinc-fingers and homeoboxes 1
  • zinc fingers and homeoboxes 1

PTMs for ZP4

Learn more about PTMs related to ZP4.

Glycosylation
Cleavage

Bioinformatics Tool for ZP4

Discover related pathways, diseases and genes to ZP4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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