ZP3 Products

Antibodies
ZP3 Antibody
ZP3 Antibody
NBP2-30830
Species: Hu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
ZP3 Antibody
ZP3 Antibody
H00007784-B01P
Species: Hu
Applications: WB
Host: Mouse Polyclonal
Lysates
ZP3 Overexpression Lysate (Na ...
ZP3 Overexpression Lysate (Native)
NBP2-09839
Applications: WB
ZP3 Overexpression Lysate (Na ...
ZP3 Overexpression Lysate (Native)
NBP2-07523
Applications: WB
ZP3 Overexpression Lysate (De ...
ZP3 Overexpression Lysate (Denatured)
H00007784-T01
Species: Hu
Applications: WB
Proteins
ZP3 Recombinant Protein Antig ...
ZP3 Recombinant Protein Antigen
NBP2-30830PEP
Species: Hu
Applications: AC
Recombinant Human ZP3 Protein ...
Recombinant Human ZP3 Protein
H00007784-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
ZP3 RNAi
ZP3 RNAi
H00007784-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

The zona pellucida is an extracellular matrix that surrounds the oocyte and early embryo. It is composed primarily of three or four glycoproteins with various functions during fertilization and preimplantation development. The protein encoded by this gene is a structural component of the zona pellucida and functions in primary binding and induction of the sperm acrosome reaction. The nascent protein contains a N-terminal signal peptide sequence, a conserved ZP domain, a C-terminal consensus furin cleavage site, and a transmembrane domain. It is hypothesized that furin cleavage results in release of the mature protein from the plasma membrane for subsequent incorporation into the zona pellucida matrix. However, the requirement for furin cleavage in this process remains controversial based on mouse studies. A variation in the last exon of this gene has previously served as the basis for an additional ZP3 locus; however, sequence and literature review reveals that there is only one full-length ZP3 locus in the human genome. Another locus encoding a bipartite transcript designated POMZP3 contains a duplication of the last four exons of ZP3, including the above described variation, and maps closely to this gene. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Product By Gene ID 7784
Alternate Names
  • zona pellucida glycoprotein 3 (sperm receptor)

Bioinformatics Tool for ZP3

Discover related pathways, diseases and genes to ZP3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.