XAF1 Products

Antibodies
XAF1 Antibody
XAF1 Antibody
NB100-56355
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
XAF1 Antibody
XAF1 Antibody
NBP1-76615
Species: Hu, Mu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
XAF1 Antibody
XAF1 Antibody
NBP2-49253
Species: Hu
Applications: IHC, IHC-P
Host: Rabbit Polyclonal
Lysates
XAF1 Overexpression Lysate (D ...
XAF1 Overexpression Lysate (Denatu...
H00054739-T01
Species: Hu
Applications: WB
XAF1 Overexpression Lysate (N ...
XAF1 Overexpression Lysate (Native)
NBL1-17897
Applications: WB
Proteins
XAF1 Recombinant Protein Anti ...
XAF1 Recombinant Protein Antigen
NBP2-49253PEP
Species: Hu
Applications: AC
XAF1 Recombinant Protein
XAF1 Recombinant Protein
NBP2-51691
Species: Hu
Applications: PAGE
XAF1 Blocking Peptide
XAF1 Blocking Peptide
NBP1-76439PEP
Species: Hu
Applications: AC
RNAi
XAF1 RNAi
XAF1 RNAi
H00054739-R01
Species: Hu
XAF1 RNAi
XAF1 RNAi
H00054739-R02
Species: Hu

Description

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 54739
Alternate Names
  • HSXIAPAF1
  • XIAPAF1XIAP-associated factor 1
  • BIRC4BPBIRC4 binding protein
  • BIRC4-binding protein
  • XIAP associated factor 1

Research Areas for XAF1

Find related products by research area and learn more about each of the different research areas below.

Apoptosis

PTMs for XAF1

Learn more about PTMs related to XAF1.

Methylation
Demethylation
Phosphorylation
Cleavage
Reduction
Ubiquitination

Bioinformatics Tool for XAF1

Discover related pathways, diseases and genes to XAF1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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