WNK3 Products

Description

Members of the 'with no lysine' (WNK) kinase family, such as WNK3, are serine-threonine protein kinases thatlack the almost invariant catalytic lysine in subdomain II, which is important for binding ATP in the catalytic site.Instead, these kinases have a conserved lysine in subdomain I that is thought to provide this function (Holden et al.,2004 (PubMed 15194194)).(supplied by OMIM)

Bioinformatics

Entrez	65267 Human
Uniprot	Q9BYP7 Human NP_065973 Human
Product By Gene ID	65267
Alternate Names	EC 2.7.11 PRKWNK3lysine deficient 3 KIAA1566FLJ42662 FLJ30437 WNK lysine deficient protein kinase 3

Diseases related to WNK3

Discover more about diseases related to WNK3.

Hypertensive Disease
Pseudohypoaldosteronism
Neoplasms
Columnar Cell Change Of The Breast
Essential Hypertension
Glioma
Neoplasm Invasiveness
Acidosis
Cleft Palate
Edema
Cell Invasion
Arthrogryposis Multiplex Congenita, Distal, Type Iia
Tissue Adhesions
Brain Neoplasms
Autistic Disorder
Neoplasm Metastasis
Neoplasms, Experimental
Anaplastic Astrocytoma

Pathways for WNK3

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Transport
Ion Transport
Secretion
Response To Osmotic Stress
Pathogenesis
Excretion
Cell Adhesion
Cell Migration
Pressure Natriuresis
Mrna Splicing
Cell Cycle
Response To Tacrolimus
Exocytosis
Secretory Pathway
Transmembrane Transport
Chloride Transport
Dna Methylation
Synaptic Transmission
Natriuresis
Endocytosis

Research Areas for WNK3

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Protein Kinase

PTMs for WNK3

Learn more about PTMs related to WNK3.

Phosphorylation
Dephosphorylation
Biotinylation
Glycosylation
Methylation

Bioinformatics Tool for WNK3

Discover related pathways, diseases and genes to WNK3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.