WIBG Products

Antibodies
WIBG Antibody (5E2)
WIBG Antibody (5E2)
Species: Hu
Applications: WB, IHC
Host: Mouse monoclonal
WIBG Antibody
WIBG Antibody
NBP1-92596
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
WIBG Antibody
WIBG Antibody
NBP2-58177
Species: Hu
Applications: ICC/IF
Host: Rabbit Polyclonal
Lysates
WIBG Overexpression Lysate (N ...
WIBG Overexpression Lysate (Native)
NBL1-17850
Applications: WB
Proteins
WIBG Recombinant Protein Anti ...
WIBG Recombinant Protein Antigen
NBP1-92596PEP
Species: Hu
Applications: AC
Recombinant Human WIBG Protei ...
Recombinant Human WIBG Protein
NBP1-45288
Species: Hu
Applications: PAGE

Description

Key regulator of the exon junction complex (EJC), a multiprotein complex that associates immediately upstreamof the exon-exon junction on mRNAs and serves as a positional landmarks for the intron exon structure of genes anddirects post-transcriptional processes in the cytoplasm such as mRNA export, nonsense-mediated mRNA decay (NMD) ortranslation. Acts as a EJC disassembly factor, allowing translation-dependent EJC removal and recycling by disruptingmature EJC from spliced mRNAs. Its association with the 40S ribosomal subunit probably prevents atranslation-independent disassembly of the EJC from spliced mRNAs, by restricting its activity to mRNAs that have beentranslated. Interferes with NMD and enhances translation of spliced mRNAs, probably by antagonizing EJC functions. Maybind RNA; the relevance of RNA-binding remains unclear in vivo, RNA-binding was detected by PubMed:14968132, whilePubMed:19410547 did not detect RNA-binding activity independently of the EJC

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 84305
Alternate Names
  • partner of Y14 and mago
  • MGC13064
  • PYMProtein wibg homolog
  • within bgcn homolog (Drosophila)

Bioinformatics Tool for WIBG

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