WDR46 Products

Description

WDR46 was originally identified as BING-4, a protein encoded in a gene-rich region of the major histocompatibility complex (MHC). WDR46 has been found to be overexpressed in a subset of melanoma cell lines and is a cancer antigen recognized by lymphocytes. WDR46 bears six WD repeats. The WD repeat is defined by four or more repeating units of a conserved core of approximately 40 amino acids ending with tryptophan-aspartic acid (WD). WD repeats may serve as sites of protein-protein interaction for adaptor proteins and facilitate multiprotein complex formation. WD proteins are involved in a variety of cellular processes. The function of WDR46 has not been characterized.

Bioinformatics

Entrez	9277 Human
Uniprot	NM_005452 Human
Product By Gene ID	9277
Alternate Names	WD repeat-containing protein 46 WD repeat-containing protein BING4 C6orf11 BING4FP221 chromosome 6 open reading frame 11 WD repeat domain 46

Diseases related to WDR46

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Neoplasm Metastasis
Malignant Neoplasms
Neoplasms
Melanoma
Asthma
Inflammation
Respiration Disorders

Pathways for WDR46

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Sensitization

Bioinformatics Tool for WDR46

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