WASP Products

Antibodies
WASP [p Ser483, p Ser484] Ant ...
WASP [p Ser483, p Ser484] Antibody
NB100-2307
Species: Hu, Canine, Equine, Primate, Rabbit, Monkey
Applications: WB
Host: Rabbit Polyclonal
WASP Antibody [Unconjugated]
WASP Antibody [Unconjugated]
AF3070
Species: Hu, Mu
Applications: WB, ICC
Host: Goat Polyclonal
WASP Antibody (336925)
WASP Antibody (336925)
MAB3070
Species: Hu
Applications: WB, ICC
Host: Mouse Monoclonal
Lysates
WASP Overexpression Lysate (N ...
WASP Overexpression Lysate (Native)
NBP2-11140
Applications: WB
Proteins
WASP Partial Recombinant Prot ...
WASP Partial Recombinant Protein
H00007454-Q01
Species: Hu
Applications: WB, ELISA, PA
WASP Recombinant Protein Anti ...
WASP Recombinant Protein Antigen
NBP1-87827PEP
Species: Hu
Applications: AC
RNAi
WASP RNAi
WASP RNAi
H00007454-R01
Species: Hu

Description

The Wiskott-Aldrich syndrome (WAS) family of proteins share similar domain structure, and are involved in transduction of signals from receptors on the cell surface to the actin cytoskeleton. The presence of a number of different motifs suggests that they are regulated by a number of different stimuli, and interact with multiple proteins. Recent studies have demonstrated that these proteins, directly or indirectly, associate with the small GTPase, Cdc42, known to regulate formation of actin filaments, and the cytoskeletal organizing complex, Arp2/3. Wiskott-Aldrich syndrome is a rare, inherited, X-linked, recessive disease characterized by immune dysregulation and microthrombocytopenia, and is caused by mutations in the WAS gene. The WAS gene product is a cytoplasmic protein, expressed exclusively in hematopoietic cells, which show signalling and cytoskeletal abnormalities in WAS patients. A transcript variant arising as a result of alternative promoter usage, and containing a different 5' UTR sequence, has been described, however, its full-length nature is not known.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 7454
Alternate Names
  • WASp
  • wiskthrombocytopenia 1 (X-linked)
  • WASP
  • IMD2THC
  • WiskTHC1

Research Areas for WASP

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Signal Transduction

PTMs for WASP

Learn more about PTMs related to WASP.

Phosphorylation
Cleavage
Dephosphorylation
Methylation
Glycosylation

Bioinformatics Tool for WASP

Discover related pathways, diseases and genes to WASP. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related WASP Blog Posts

Check out the latest blog posts on WASP.
"Actin the Fool" about Cytoskeleton Structure
Actins are highly conserved, commonly found and abundant proteins involved in several types of cell motility as well as cytoskeleton maintenance. In vertebrate species, three main groups of actin isoforms, the alpha, beta and gamma, have been identifi...    Read more.
Read more WASP related blogs.