VAMP4 Products

Description

The vesicle associated membrane proteins (VAMP) or synaptobrevins are calcium binding proteins specific to eukaryotes. VAMPs, along with synaptosomal associated protein of 25 kDa (SNAP 25) and syntaxin, form the core complex of soluble NSF attachment protein receptor (SNARE) proteins that interact with the soluble proteins N-ethylmaleimide-sensitive factor (NSF) and alpha-SNAP. These membrane associated proteins play a key role in the regulation of vesicle membrane fusion with the plasma membrane. The Clostridium tetani neurotoxin is a metalloprotease with specificity for VAMP. In Alzheimer®s disease, VAMP levels of all isoforms appear to be significantly lowered.

Bioinformatics

Entrez	364033 Rat 53330 Mouse 8674 Human
Uniprot	AAH31264 Human NM_003762 Human NP_003753 Human O75553 Human
Product By Gene ID	8674
Alternate Names	VAMP24 VAMP-4 vesicle-associated membrane protein 4

Research Areas for VAMP4

Find related products by research area and learn more about each of the different research areas below.

Membrane Trafficking and Chaperones
Membrane Vesicle Markers
Neuronal Cell Markers
Neurotransmission
Phospho-Specific