UVRAG Products

Antibodies
UVRAG Antibody
UVRAG Antibody
NBP2-24482
Species: Hu, Mu, Rt, Ca, Ch, Pm
Applications: WB
Host: Rabbit Polyclonal
UVRAG Antibody
UVRAG Antibody
NBP1-18885
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Host: Rabbit Polyclonal
UVRAG Antibody (2E8.)
UVRAG Antibody (2E8.)
H00007405-M04
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Lysates
UVRAG Overexpression Lysate ( ...
UVRAG Overexpression Lysate (Native)
NBL1-17684
Applications: WB
UVRAG Overexpression Lysate ( ...
UVRAG Overexpression Lysate (Denat...
H00007405-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human UVRAG Prote ...
Recombinant Human UVRAG Protein
H00007405-P01
Species: Hu
Applications: WB, ELISA, PA
Recombinant Human UVRAG Prote ...
Recombinant Human UVRAG Protein
H00007405-Q01
Species: Hu
Applications: WB, ELISA, PA
UVRAG Recombinant Protein Ant ...
UVRAG Recombinant Protein Antigen
NBP1-86861PEP
Species: Hu
Applications: AC

Description

UVRAG complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq]

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Human
Product By Gene ID 7405
Alternate Names
  • DHTX
  • UV radiation resistance-associated gene protein
  • p63
  • disrupted in heterotaxy
  • VPS38
  • beclin 1 binding protein
  • UV radiation resistance associated gene

PTMs for UVRAG

Learn more about PTMs related to UVRAG.

Phosphorylation
Cleavage
Ubiquitination

Bioinformatics Tool for UVRAG

Discover related pathways, diseases and genes to UVRAG. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related UVRAG Blog Posts

Check out the latest blog posts on UVRAG.
UVRAG - A regulator of membrane trafficking in autophagy and endocytosis
UV resistance-associated gene (UVRAG) is a tumor suppressor that is commonly mutated in colon and breast cancer. While UVRAG was discovered for its ability to complement UV sensitivity in xeroderma pigmentosum cells, its main functions are in auto...    Read more.
TFEB - An essential regulator of lysosome biogenesis
Transcription factor EB (TFEB) is a member of the MiTF/TFE (Microphthalmia/TFE) subfamily of basic/helix-loop-helix/leucine zipper transcription factors. This group of proteins is involved in the proliferation and development of specific cell type...    Read more.
Beclin 2, a mammal-specific homolog of Beclin 1 with unique functional similarities and differences
Beclin 2 (BECN2) is also called Beclin-1-like protein 1/ BECN1P1 and it was recently identified by He et al 2013 as a mammal-specific homolog of the evolutionarily conserved protein Beclin 1 which is well established for its role in the regulation...    Read more.
Read more UVRAG related blogs.