UGT2A1 Products

Description

The protein encoded by this gene belongs to the UDP-glycosyltransferase family. Members of this protein family play a role in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. The encoded enzyme is expressed in the olfactory neuroepithelium, which lines the posterior nasal cavity and is exposed to a wide range of odorants and airborne toxic compounds. Hence, this protein has been suggested to be involved in clearing lipophilic odorant molecules from the sensory epithelium. This gene shares exon structure with the UDP glucuronosyltransferase 2A2 family member, which encodes N-terminally distinct isoforms. Polymorphisms in this gene may be associated with the loss of taste and smell that is reported by some individuals during SARS-CoV-2 infection.

Bioinformatics

Entrez	574537 Human
Uniprot	NP_006789 Human
Product By Gene ID	10941
Alternate Names	UDP glucuronosyltransferase 2 family, polypeptide A1, complex locus UDP glycosyltransferase 2 family, polypeptide A1 UDP-glucuronosyltransferase 2A1 UDPGT2A1 uridine diphosphate glycosyltransferase 2 family, member A1