Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: AC
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes.
Bioinformatics
| Entrez |
Human
Mouse
|
| Uniprot |
Human
Human
Human
|
| Product By Gene ID |
10277 |
| Alternate Names |
- E4
- homologous to yeast UFD2
- Homozygously deleted in neuroblastoma 1
- homozygously deleted in neuroblastoma-1
- KIAA0684HDNB1
- ubiquitin conjugation factor E4 B
- Ubiquitin fusion degradation protein 2
- ubiquitination factor E4B (homologous to yeast UFD2)
- ubiquitination factor E4B (UFD2 homolog, yeast)
- ubiquitin-fusion degradation protein 2
- UBOX3
- UFD2UFD2A
|
Research Areas for UBE4B
Find related products by research area and learn more about each of the different research areas below.
Apoptosis
