UBA3 Products

Antibodies
UBA3 Antibody
UBA3 Antibody
NBP1-83150
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UBA3 Antibody
UBA3 Antibody
NBP2-49443
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
UBA3 Antibody
UBA3 Antibody
NBP2-48628
Species: Hu
Applications: WB, IHC
Host: Rabbit Polyclonal
Lysates
UBA3 Overexpression Lysate (N ...
UBA3 Overexpression Lysate (Native)
NBL1-17498
Applications: WB
UBA3 Overexpression Lysate (N ...
UBA3 Overexpression Lysate (Native)
NBL1-17497
Applications: WB
Proteins
UBA3 Recombinant Protein Anti ...
UBA3 Recombinant Protein Antigen
NBP1-83150PEP
Species: Hu
Applications: AC
UBA3 Recombinant Protein Anti ...
UBA3 Recombinant Protein Antigen
NBP2-48628PEP
Species: Hu
Applications: AC
UBA3 Recombinant Protein Anti ...
UBA3 Recombinant Protein Antigen
NBP2-49443PEP
Species: Hu
Applications: AC

Description

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 9039
Alternate Names
  • EC 6.3.2
  • DKFZp566J164
  • Ubiquitin-activating enzyme E1C
  • hUba3
  • EC 6.3.2.-
  • NEDD8-activating enzyme E1C
  • UBA3, ubiquitin-activating enzyme E1 homolog
  • UBE1C
  • Nedd8-activating enzyme hUba3
  • Ubiquitin-like modifier-activating enzyme 3
  • NEDD8-activating enzyme E1 catalytic subunit
  • Ubiquitin-activating enzyme 3
  • hUBA3
  • yeast)
  • ubiquitin-activating enzyme E1C (homologous to yeast UBA3)
  • MGC22384
  • ubiquitin-like modifier activating enzyme 3

Research Areas for UBA3

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cell Cycle and Replication
Neuroscience

PTMs for UBA3

Learn more about PTMs related to UBA3.

Ubiquitination
Phosphorylation

Bioinformatics Tool for UBA3

Discover related pathways, diseases and genes to UBA3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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