TRIM5 gamma Products

Antibodies
TRIM5 gamma Antibody
TRIM5 gamma Antibody
NBP1-76604
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal

Description

TRIM5 is a member of a broad family of otherwise unrelated proteins defined by the presence of a tripartite motif containing a RING domain, a B-box type 1, and a B-box type 2, followed by a coiled-coil region (1). TRIM5 has five alternately spliced isoforms, the longest of which is the alpha variant which also contains a carboxy-terminal B30.2 (SPRY) domain (1). While a function has not yet been assigned to TRIM5gamma, it is known that expression of TRIM5alpha variants from humans, rhesus monkeys, and African green monkeys enable resistance to infection by various retroviruses including HIV-1 (2,3), albeit at differing efficiencies. Furthermore, the TRIM5delta isoform appears to serve as a scaffold for the assembly of endogenous BTBD1 and BTBD2 proteins and also exhibits autoubiquitination activity in a RING finger- and UbcH5B-dependent manner (4).

Bioinformatics

Uniprot Human
Product By Gene ID 85363
Alternate Names
  • EC 6.3.2
  • EC 6.3.2.-
  • RING finger protein 88
  • tripartite motif-containing protein 5
  • tripartite motif-containing 5
  • tripartite motif protein TRIM5
  • TRIM5alpha
  • RNF88tripartite motif protein TRIM
  • tripartite motif containing 5

Research Areas for TRIM5 gamma

Find related products by research area and learn more about each of the different research areas below.

Immunology
Lipid and Metabolism
Virology, Bacteria and Parasites
Zinc Finger

PTMs for TRIM5 gamma

Learn more about PTMs related to TRIM5 gamma.

Ubiquitination
Sumoylation
Cleavage

Bioinformatics Tool for TRIM5 gamma

Discover related pathways, diseases and genes to TRIM5 gamma. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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