Transglutaminase 1/TGM1 Products

Description

Tissue transglutaminase is a calcium activated enzyme which catalyzes the cross linking of proteins and the conjugation of polyamines to proteins. The identification of transglutaminase as the main antigen of endomysium antibodies allows a new diagnostic approach to celiac disease (CD). CD, a genetic, immunologically mediated small bowel enteropathy that causes malabsorption, is one of the more common disorders in Western countries.

Bioinformatics

Entrez	7051 Human 21818 Mouse 366189 Rat
Uniprot	AAH34699 Human NP_000350.1 Human NM_000359 Human P22735 Human
Product By Gene ID	7051
Alternate Names	TG(K) Transglutaminase-1 KTG transglutaminase-1 Transglutaminase K transglutaminase, keratinocyte Epidermal TGase protein-glutamine gamma-glutamyltransferase K TGASE ICR2 LI LI1EC 2.3.2.13 TGKTGase K TGase-1 protein-glutamine-gamma-glutamyltransferase) transglutaminase 1 (K polypeptide epidermal type I

Diseases related to Transglutaminase 1/TGM1

Discover more about diseases related to Transglutaminase 1/TGM1.

Ichthyoses
Congenital Nonbullous Ichthyosiform Erythroderma
Congenital Ichthyosis
Exfoliative Dermatitis
Ichthyosiform Erythroderma, Congenital
Dermatologic Disorders
Hyperkeratosis
Harlequin Fetus
Erythema
Skin Diseases, Genetic
Metaplasia
Swine Diseases
Dysequilibrium Syndrome
Psoriasis
Disorder Of Keratinization
Inflammation
Dermatitis, Atopic

Pathways for Transglutaminase 1/TGM1

View related products by pathway and learn more about each of the pathways below.

Keratinization
Cornification
Localization
Immune Response
Pathogenesis
Coagulation
Transport
Cell Adhesion
Transposition
Chromosome Localization
Programmed Cell Death
Proteolysis
Response To Vitamin
Keratinocyte Differentiation
Response To Vitamin A
Reverse Transcription
Translation
Response To Retinoic Acid
Cell Death
Antigen Processing And Presentation

PTMs for Transglutaminase 1/TGM1

Learn more about PTMs related to Transglutaminase 1/TGM1.

Deamination
Biotinylation
Methylation
Palmitoylation
Myristoylation

Bioinformatics Tool for Transglutaminase 1/TGM1

Discover related pathways, diseases and genes to Transglutaminase 1/TGM1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.