Topo III beta Products

Antibodies
Topo III beta Antibody
Topo III beta Antibody
NB100-92303
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Topo III beta Antibody (1H4)
Topo III beta Antibody (1H4)
H00008940-M04
Species: Hu
Applications: WB, ELISA, ICC/IF
Host: Mouse Monoclonal
Topo III beta Antibody (4F11) ...
Topo III beta Antibody (4F11)
H00008940-M01
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Topo III beta Overexpression ...
Topo III beta Overexpression Lysat...
H00008940-T01
Species: Hu
Applications: WB
Topo III beta Overexpression ...
Topo III beta Overexpression Lysat...
H00008940-T02
Applications: WB
Proteins
Topo III beta Recombinant Pro ...
Topo III beta Recombinant Protein
H00008940-P01
Species: Hu
Applications: WB, ELISA, PA
RNAi
Topo III beta RNAi
Topo III beta RNAi
H00008940-R01V
Species: Hu
Applications: WB, RNAi SP
Topo III beta RNAi
Topo III beta RNAi
H00008940-R01
Species: Hu

Description

Topo III beta encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus relaxing the supercoils and altering the topology of DNA. The enzyme interacts with DNA helicase SGS1 and plays a role in DNA recombination, cellular aging and maintenance of genome stability. Alternative splicing of the C-terminus of this gene results in three transcript variants which have distinct tissue specificity; however, not all variants have been fully described.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Product By Gene ID 8940
Alternate Names
  • TOP3B1
  • EC 5.99.1.2
  • FLJ39376
  • topoisomerase III beta
  • DNA topoisomerase III beta-1
  • DNA topoisomerase 3-beta-1
  • topoisomerase (DNA) III beta

Pathways for Topo III beta

View related products by pathway and learn more about each of the pathways below.

Dna Replication
Dna Repair
Drug Resistance
Telomere Maintenance
Aging

Research Areas for Topo III beta

Find related products by research area and learn more about each of the different research areas below.

Apoptosis
Cancer
Cell Cycle and Replication
Core ESC-Like Genes
DNA Double Strand Break Repair
DNA Repair
Hypoxia
Stem Cell Markers
Transcription Factors and Regulators
Tumor Suppressors

Bioinformatics Tool for Topo III beta

Discover related pathways, diseases and genes to Topo III beta. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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