Thymidine Kinase 1 Products

Antibodies
Thymidine Kinase 1 Antibody
Thymidine Kinase 1 Antibody
NBP2-20626
Species: Hu, Mu, Rt, Bv
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Thymidine Kinase 1 Antibody
Thymidine Kinase 1 Antibody
NB100-60644
Species: Hu
Applications: WB, IP
Host: Rabbit Polyclonal
Thymidine Kinase 1 Antibody ( ...
Thymidine Kinase 1 Antibody (3F9)
H00007083-M05
Species: Hu
Applications: WB, ELISA
Host: Mouse Monoclonal
Lysates
Thymidine Kinase 1 Overexpres ...
Thymidine Kinase 1 Overexpression ...
H00007083-T01
Species: Hu
Applications: WB
Proteins
Recombinant Human Thymidine K ...
Recombinant Human Thymidine Kinase...
NBP1-98920
Species: Hu
Applications: PAGE
RNAi
Thymidine Kinase 1 RNAi
Thymidine Kinase 1 RNAi
H00007083-R01V
Species: Hu
Applications: WB, RNAi, RNAi SP
Thymidine Kinase 1 RNAi
Thymidine Kinase 1 RNAi
H00007083-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Thymidine kinase (TK) belongs to a group of enzymes such as dihydrofolate reductase, thymidylate synthase, and DNA polymerase that are involved in DNA synthesis and precursor production. Two forms have been identified in animal cells, one in cytosol and one in mitochondria. Activity of the cytosolic enzyme is high in proliferating cells and peaks during the S-phase of the cell cycle; it is very low in resting cells due to multiple regulatory mechanisms that ensure expression of these enzymes exclusively in replicating cells. TK is responsible for catalyzing the phosphorylation of thymidine, which functions as a part of the pyrimidine salvage pathway involved in DNA synthesis. The activities of enzymes such as TK are essential for the activation of several chemotherapeutically important nucleoside analogues that are administered as prodrugs.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 7083
Alternate Names
  • thymidine kinase-1
  • thymidine kinase, cytosolic
  • thymidine kinase 1 soluble isoform
  • TK2
  • EC 2.7.1.21
  • thymidine kinase 1, soluble

Research Areas for Thymidine Kinase 1

Find related products by research area and learn more about each of the different research areas below.

DNA Repair
DNA replication, Transcription, Translation and Splicing
Stem Cell Markers

PTMs for Thymidine Kinase 1

Learn more about PTMs related to Thymidine Kinase 1.

Phosphorylation
Deamination
Acetylation
Dephosphorylation
Ubiquitination
Biotinylation
Iodination

Bioinformatics Tool for Thymidine Kinase 1

Discover related pathways, diseases and genes to Thymidine Kinase 1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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