TEP1 Products

Antibodies
TEP1 Antibody
TEP1 Antibody
NBP1-77285
Species: Hu, Mu, Rt
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, IF
Host: Rabbit Polyclonal
TEP1 Antibody
TEP1 Antibody
NBP1-03224
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
Proteins
Recombinant Human TEP1 Protei ...
Recombinant Human TEP1 Protein
H00007011-Q01
Species: Hu
Applications: WB, ELISA, PA
TEP1 Blocking Peptide
TEP1 Blocking Peptide
NBP1-77285PEP
Species: Hu
Applications: AC
RNAi
TEP1 RNAi
TEP1 RNAi
H00007011-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

Telomerase is an RNA-dependent DNA polymerase that uses an RNA component to add telomeric repeat sequences at the ends of chromosomes. Besides the RNA component which serves as the template that specifies the telomeric repeat, the telomerase complex contains a reverse transcriptase protein (TRT) and various accessory proteins including the telomerase-associated protein 1 (TP1). Telomerase activity is low in most somatic cells, causing the gradual shortening of telomeres which can ultimately lead to telomere fusion and cell death. High levels of telomerase activity are widely seen in cancerous cells and while recent experiments have suggested that telomerase may be a viable target in cancer therapy, expression levels of TP1 do not correlate with malignancy. At least two isoforms of TP1 are known to exist.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 7011
Alternate Names
  • TROVE domain family, member 1
  • TROVE1
  • p240telomerase protein component 1
  • TLP1p80 telomerase homolog
  • TP1Telomerase protein 1
  • telomerase-associated protein 1VAULT2

PTMs for TEP1

Learn more about PTMs related to TEP1.

Phosphorylation
Dephosphorylation
Cleavage
Methylation
Nitration
Glycosylation

Bioinformatics Tool for TEP1

Discover related pathways, diseases and genes to TEP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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