Tec Products

Antibodies
Tec Antibody (663921)
Tec Antibody (663921)
MAB6519
Species: Hu, Mu
Applications: WB, IHC
Host: Mouse Monoclonal
Tec Antibody
Tec Antibody
NBP1-87206
Species: Hu, Mouse, Rat
Applications: WB, ICC/IF, IHC, IHC-P
Host: Rabbit Polyclonal
Tec Antibody
Tec Antibody
NBP2-20592
Species: Hu
Applications: WB
Host: Rabbit Polyclonal
Lysates
Tec Overexpression Lysate (Na ...
Tec Overexpression Lysate (Native)
NBP2-08029
Applications: WB
Proteins
Tec Partial Recombinant Prote ...
Tec Partial Recombinant Protein
H00007006-Q01
Species: Hu
Applications: WB, ELISA, PA
Tec Recombinant Protein Antig ...
Tec Recombinant Protein Antigen
NBP1-87206PEP
Species: Hu
Applications: AC
RNAi
Tec RNAi
Tec RNAi
H00007006-R02
Species: Hu
Applications: RNAi, RNAi SP

Description

Tec is a member of the Tec family of non-receptor protein-tyrosine kinase (PTK) which also includes Btk, emtk/itk/Tsk, Rlk/Txx and Bmx (1). Tec is composed of a pleckstrin domain (PH), an SH3 and SH2 domain, a catalytic kinase domain and a Tec homology domain (TH) (2). Tec's TH domain interacts with the SH3 domain of Grb2, Src family PTKs (Fyn, Lyn, and Hck), Vav, and c-Kit. Tec is mostly expressed in hematopoietic cells. Tec's SH3 domain interacts with DC28 and has been shown to phosphorylate p62dok, CD28 substrate (3). Tec can phosphorylate Jak kinase in hematopoietic cells (4) and can also be phosphorylated by Src member Lyn on multiple tyrosine residues (5).

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 7006
Alternate Names
  • MGC126760
  • EC 2.7.10
  • EC 2.7.10.2
  • PSCTK4tyrosine-protein kinase Tec
  • MGC126762
  • tec protein tyrosine kinase

Research Areas for Tec

Find related products by research area and learn more about each of the different research areas below.

Protein Kinase

Bioinformatics Tool for Tec

Discover related pathways, diseases and genes to Tec. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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