TAT Products

Antibodies
TAT Antibody
TAT Antibody
46420002
Species: Hu
Applications: WB, ELISA
Host: Rabbit Polyclonal
TAT Antibody
TAT Antibody
NBP1-79286
Species: Rt
Applications: WB
Host: Rabbit Polyclonal
ELISA Kits
TAT ELISA Kit [Biotin]
TAT ELISA Kit [Biotin]
KA1857
Species: Mu
TAT ELISA Kit [Biotin]
TAT ELISA Kit [Biotin]
KA0508
Species: Hu
Lysates
TAT Overexpression Lysate (Na ...
TAT Overexpression Lysate (Native)
NBP2-09032
Applications: WB

Description

The transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator response element, located at the end of the HIV genetic chain. There, the tat protein helps assemble new copies of HIV. The tat protein-TAR complex speeds up the rate of viral reproduction by about a thousand times. If it is not present, the transcription process frequently stops short, and few functional HIV particles are produced. Tat is an important potential target for antiretrovirals and vaccine development. Transcriptional regulator that acts by binding to the trans-activating responsive sequence (TAR) RNA element and activates transcription initiation and/or elongation from the LTR promoter.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Product By Gene ID 6898
Alternate Names
  • tyrosine aminotransferase, cytosolic
  • EC 2.6.1.5
  • L-tyrosine:2-oxoglutarate aminotransferase
  • tyrosine aminotransferase

Bioinformatics Tool for TAT

Discover related pathways, diseases and genes to TAT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related TAT Blog Posts

Check out the latest blog posts on TAT.
Understanding Transcription with RNA Polymerase II
RNA polymerase II is a large 12-subunit complex that synthesizes all mRNAs and several non-coding RNAs in eukaryotic cells. It is a DNA-dependent RNA polymerase enzyme that catalyzes transcription of DNA into RNA based on the four ribonucleoside triph...    Read more.
Read more TAT related blogs.