TAT Products

TAT Antibody
TAT Antibody
Species: Rt
Applications: WB
Host: Rabbit Polyclonal
TAT Antibody
TAT Antibody
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
Host: Rabbit Polyclonal
TAT Overexpression Lysate
TAT Overexpression Lysate
Species: Hu
Applications: WB


The transcriptional transactivator (Tat) is a key regulatory protein of HIV. It is expressed early after the virus integrates into the cell, and stimulates the elongation of RNA polymerase II. It binds onto a sequence known as the TAR, or transactivator response element, located at the end of the HIV genetic chain. There, the tat protein helps assemble new copies of HIV. The tat protein-TAR complex speeds up the rate of viral reproduction by about a thousand times. If it is not present, the transcription process frequently stops short, and few functional HIV particles are produced. Tat is an important potential target for antiretrovirals and vaccine development. Transcriptional regulator that acts by binding to the trans-activating responsive sequence (TAR) RNA element and activates transcription initiation and/or elongation from the LTR promoter.


Entrez Human
Uniprot Human
Product By Gene ID 6898
Alternate Names
  • tyrosine aminotransferase, cytosolic
  • EC
  • L-tyrosine:2-oxoglutarate aminotransferase
  • tyrosine aminotransferase

Bioinformatics Tool for TAT

Discover related pathways, diseases and genes to TAT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Vizit™, under license from BioVista Inc.

Related TAT Blog Posts

Check out the latest blog posts on TAT.
Methamphetamine with HIV induces mitochondrial dysfunction and neuronal injury through oxidative stress
By Jamshed Arslan, Pharm. D., PhD. December 1 is the World AIDS Day. Despite the combination antiretroviral therapy, 10-25% of Human Immunodeficiency Virus (HIV)-positive individuals report neurocognitive impairm...    Read more.
Understanding Transcription with RNA Polymerase II
RNA polymerase II is a large 12-subunit complex that synthesizes all mRNAs and several non-coding RNAs in eukaryotic cells. It is a DNA-dependent RNA polymerase enzyme that catalyzes transcription of DNA into RNA based on the four ribonucleoside triph...    Read more.
Read more TAT related blogs.