TAF6L Products

Description

Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is a component of the PCAF histone acetylase complex and structurally similar to one of the histone-like TAFs, TAF6. The PCAF histone acetylase complex, which is composed of more than 20 polypeptides some of which are TAFs, is required for myogenic transcription and differentiation.

Bioinformatics

Entrez	10629 Human
Uniprot	NP_006464 Human Q9Y6J9 Human
Product By Gene ID	10629
Alternate Names	FLJ11136 p300/CBP-associated factor (PCAF)-associated factor 65 PAF65-alpha PAF65AMGC4288 PCAF-associated factor 65 alpha PCAF-associated factor 65-alpha TAF6-like RNA polymerase II p300/CBP-associated factor-associated factor 65 kDasubunit 6L TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associatedfactor, 65 kD TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associatedfactor, 65kDa