SUPT16H Products

Description

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. (provided by RefSeq)

Bioinformatics

Entrez	11198 Human
Uniprot	NP_009123 Human NP_009123.1 Human Q9Y5B9 Human
Product By Gene ID	11198
Alternate Names	CDC68 Chromatin-specific transcription elongation factor 140 kDa subunit facilitates chromatin remodeling 140 kDa subunit Facilitates chromatin transcription complex subunit SPT16 FACT 140 kDa subunit FACT complex subunit SPT16 FACT140 FACTp140 FACTP140FACT FLJ10857 FLJ14010 FLJ34357 hSPT16 SPT16/CDC68 suppressor of Ty (S.cerevisiae) 16 homolog suppressor of Ty 16 homolog (S. cerevisiae)