SUPT16H Antibody (OTI3B8) [Janelia Fluor® 549]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI3B8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Janelia Fluor 549

SUPT16H Antibody (OTI3B8) [Janelia Fluor® 549] Summary

• Immunogen: Human recombinant protein fragment corresponding to amino acids 187-282 of human SUPT16H (NP_009123) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SUPT16H
• Purity: >95%

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: >95%

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for SUPT16H Antibody (OTI3B8) [Janelia Fluor® 549]

• CDC68
• Chromatin-specific transcription elongation factor 140 kDa subunit
• facilitates chromatin remodeling 140 kDa subunit
• Facilitates chromatin transcription complex subunit SPT16
• FACT 140 kDa subunit
• FACT complex subunit SPT16
• FACT140
• FACTp140
• FACTP140FACT
• FLJ10857
• FLJ14010
• FLJ34357
• hSPT16
• SPT16/CDC68
• suppressor of Ty (S.cerevisiae) 16 homolog
• suppressor of Ty 16 homolog (S. cerevisiae)

Background

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II. However, this minimal system cannot transcribe DNA packaged into chromatin, indicating that accessory factors may facilitate access to DNA. One such factor, FACT (facilitates chromatin transcription), interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT is composed of an 80 kDa subunit and a 140 kDa subunit; this gene encodes the 140 kDa subunit. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SUPT16H