STAM-1 Products

Antibodies
Antibody Pairs
STAM-1 Antibody Pair
STAM-1 Antibody Pair
H00008027-PW1
Species: Hu
Applications: WB, IP
Lysates
STAM-1 Knockout 293T Cell Lys ...
STAM-1 Knockout 293T Cell Lysate
NBP2-78685
Species: Hu
STAM-1 Overexpression Lysate
STAM-1 Overexpression Lysate
NBP2-08004
Species: Hu
Applications: WB
Proteins
Recombinant Human STAM-1 Prot ...
Recombinant Human STAM-1 Protein, CF
E-550
Species: Hu
Applications: Enzyme Activity
Formulation Catalog # Availability Price  
STAM-1 Recombinant Protein An ...
STAM-1 Recombinant Protein Antigen
NBP2-38514PEP
Species: Hu
Applications: AC

Description

STAM was identified by the rapid tyrosine-phosphorylation of its product in response to cytokine stimulation. The encoded protein contains a SH3 domain and the immunoreceptor tyrosine-based activation motif (ITAM). This protein associates with JAK3 and JAK2 kinases via its ITAM region, and is phosphorylated by the JAK kinases upon cytokine stimulation, which suggests the function of this protein is as an adaptor molecule involved in the downstream signaling of cytokine receptors. HGS/HRS (hepatocyte grwoth factor-regulated tyrosine kinase substrate) has been found to bind and counteract the function of this protein.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Human
Product By Gene ID 8027
Alternate Names
  • signal transducing adapter molecule 1
  • HSE1 homolog
  • DKFZp686J2352
  • STAM1STAM-1
  • signal transducing adaptor molecule (SH3 domain and ITAM motif) 1

PTMs for STAM-1

Learn more about PTMs related to STAM-1.

Ubiquitination
Phosphorylation
Ribosylation
Cleavage
Nitration

Bioinformatics Tool for STAM-1

Discover related pathways, diseases and genes to STAM-1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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