SSRP1 Products

Description

SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D7 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.

Bioinformatics

Entrez	6749 Human
Uniprot	NP_003137 Human NP_003137.1 Human Q08945 Human
Product By Gene ID	6749
Alternate Names	Chromatin-specific transcription elongation factor 80 kDa subunit cisplatin-DNA SSRP facilitates chromatin remodeling 80 kDa subunit Facilitates chromatin transcription complex 80 kDa subunit Facilitates chromatin transcription complex subunit SSRP1 FACT complex subunit SSRP1 FACT FACT80FACT 80 kDa subunit FACTp80 high mobility group box hSSRP1 Recombination signal sequence recognition protein 1 structure specific recognition protein 1 Structure-specific recognition protein 1 T160