SSRP1 Products

Description

SSRP1 is a nuclear protein and a component of the FACT complex (facilitates chromatin transcription). The FACT complex is composed of the SUPT16H (FACT140) and the SSRP1 FACTp80 proteins. This complex interacts with nucleosomes and histone H2A/H2B dimers to promote nucleosome disassembly and allow transcription elongation. This protein interacts with dsDNA. The SSRP1 protein has been shown to be modified by cisplatin and may protect DNA from repair and block DNA replication. The 10D7 monoclonal antibody recognizes the human SSRP1 protein and has been shown to be useful for Western blotting.

Bioinformatics

Entrez	6749 Human
Uniprot	Q08945 Human NP_003137 Human NP_003137.1 Human
Product By Gene ID	6749
Alternate Names	high mobility group box FACTp80 FACT complex subunit SSRP1 Structure-specific recognition protein 1 facilitates chromatin remodeling 80 kDa subunit Recombination signal sequence recognition protein 1 cisplatin-DNA SSRP Facilitates chromatin transcription complex subunit SSRP1 FACT Facilitates chromatin transcription complex 80 kDa subunit hSSRP1 Chromatin-specific transcription elongation factor 80 kDa subunit FACT80FACT 80 kDa subunit T160 structure specific recognition protein 1

Diseases related to SSRP1

Discover more about diseases related to SSRP1.

Neoplasms
Malignant Neoplasms
Carcinoma
Ovarian Neoplasm
Sclerosis
Diffuse Scleroderma
Lupus Erythematosus, Systemic
Rheumatoid Arthritis
Autoimmune Diseases
Arthritis
Malignant Neoplasm Of Lung
Cell Transformation, Neoplastic
Autoimmune Reaction
Cholangiocarcinoma
Permissiveness, Biological Function
Malignant Neoplasm Of Breast
Werner Syndrome
Swine Diseases
Churg-strauss Syndrome

Pathways for SSRP1

View related products by pathway and learn more about each of the pathways below.

Dna Replication
Cell Cycle
Chromatin Remodeling
Dna Repair
Interphase
Localization
Cell Differentiation
Cell Proliferation
S Phase
Chromosome Segregation
Dna Replication Initiation
Nucleosome Disassembly
Mitosis
Cell Death
Cell Growth
Rna Interference
Transport
Cell Cycle Checkpoint
Proteolysis
Dna Demethylation

PTMs for SSRP1

Learn more about PTMs related to SSRP1.

Phosphorylation
Cleavage
Methylation
Sumoylation
Demethylation
Acetylation
Dephosphorylation
Ribosylation

Bioinformatics Tool for SSRP1

Discover related pathways, diseases and genes to SSRP1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.