SSH2 Products

Description

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002 [PubMed 11832213]).[supplied by OMIM]

Bioinformatics

Entrez	85464 Human
Uniprot	AAH11636.2 Human NP_203747 Human
Product By Gene ID	85464
Alternate Names	EC 3.1.3.16 EC 3.1.3.48 hSSH-2L KIAA1725protein phosphatase Slingshot homolog 2 MGC78588 slingshot 2 slingshot homolog 2 (Drosophila) SSH-2 SSH2L SSH-2L SSH-like protein 2

Diseases related to SSH2

Discover more about diseases related to SSH2.

Neoplasms
Cell Invasion
Stomach Neoplasms
Neoplasm Metastasis
Mutation, Out-of-frame
Neointima
Liver Carcinoma
High-frequency Microsatellite Instability
Tissue Adhesions
Microsatellite Instability
Neoplasm Invasiveness
Carcinoma
Vascular System Injuries
Malignant Neoplasm Of Stomach
Malignant Neoplasms
Posttransfusion Purpura
Colorectal Neoplasms
Formation, Neointima
Colorectal Cancer
Low-frequency Microsatellite Instability

Pathways for SSH2

View related products by pathway and learn more about each of the pathways below.

Cell Migration
Protein Phosphorylation
Actin Cytoskeleton Organization
Cytoskeleton Organization
Keratinocyte Migration
Muscle Cell Migration
Smooth Muscle Cell Migration
Wound Healing
Virulence
Rna Interference

Research Areas for SSH2

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Protein Phosphatase

PTMs for SSH2

Learn more about PTMs related to SSH2.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for SSH2

Discover related pathways, diseases and genes to SSH2. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.