SPNS1 Products

Description

SPNS1 is a human ortholog of the Drosophila melanogaster spin gene. Many orthologs have been identified in a number of species from nematodes to humans. In drosophila the Spin protein may function in mediating apoptotic signals conveyed from follicle cells to nurse cells or from glia to neurons. The accumulation of lipofuscin-like materials in spin mutant neurons further implies the possible function of the spin gene in regulating lysosomal turnover in nerve cells. SPNS1 may be involved in necrotic or autophagic cell death.

Bioinformatics

Entrez	73658 Mouse 83985 Human
Uniprot	NP_001135920 Human NP_114427 Human Q9H2V7 Human
Product By Gene ID	83985
Alternate Names	FLJ38358 HSpin1Spinster-like protein 1 LAT PP2030 protein spinster homolog 1 SPIN1nrs SPINL spinster homolog 1 (Drosophila)