SPG7 Products

Description

This gene encodes a nuclear-encoded mitochondrial metalloprotease protein that is a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 7. [provided by RefSeq]. Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.

Bioinformatics

Product By Gene ID	6687
Alternate Names	CARMGC126331 cell matrix adhesion regulator CMARMGC126332 EC 3.4.24 EC 3.4.24.- FLJ37308 paraplegin PGNcell adhesion regulator spastic paraplegia 7 (pure and complicated autosomal recessive) Spastic paraplegia 7 protein SPG5C

Research Areas for SPG7

Find related products by research area and learn more about each of the different research areas below.

Cell Biology
Neurodegeneration
Neuroscience